Thinking Outside the Shortlist for Women in Comedy

Margaret here with a guessing game for you: a studio comedy is in production, and the lead is a woman. Who gets cast? If you're a Hollywood executive, the answer is Tina Fey, Melissa McCarthy, Kristen Wiig or Jennifer Aniston. Looking at today's top-grossing movies, you'd be forgiven for thinking that there are only four comic leading ladies; the studio focus on bankability keeps them sticking to a pretty rigid shortlist.
I am in no way saying that the women on the funny-lady short lists aren’t funny; they absolutely are! This is just a gentle reminder that there are other bankable comediennes out there, and that creative casting pays off, (Orange is the New Black, anyone?) because it can oftentimes elevate so-so material. Casting is like dessert: no one really knows what they want until you roll the cart by and show it to them.
Orange Is the New Black's cast of unknowns spun comedy gold. It can happen again.
McLendon-Covey's suggestions include: casting that all-female Ghostbusters reboot with Carrie Brownstein, Michaela Watkins, and Regina Hall; bringing together Laurie Metcalf, Jane Lynch, and Shondrella Avery as state college professors competing for the same research grant; pairing Gabourey Sidibe and Edi Patterson as proprietors of a marijuana dispensary / cat sanctuary who are looking for love; and putting Ellie Kemper and Jane Krakowski together as process servers who go around breaking hearts.
(Personally, I would love a movie where Kate McKinnon, Danielle Brooks, Christine Baranski, and Casey Wilson all have a bottomless mimosa brunch with me. Selfish? Probably.)